The more and more I think about it, the more and more I like the idea of a rant show. It may not be episode 50, but there's a good chance we might have an all-rant episode à la the all-vampire, all-Muppets and all-cartoon shows we've already produced.
Cool.
If 50 isn't the rant show then how about a "50 favourite" things episode? 2 hours, countdown from 50 to 1 (being nice enough to compromise with Jenny of course) describing why you love these things (comics, characters, stories, novels, video games, toys, statues, etc....)